MTRR Protein (AA 1-725, full length) (GST tag)
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- Target See all MTRR Proteins
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-725
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MTRR protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGAASVRAGA RLVEVALCSF TVTCLEVMRR FLLLYATQQG QAKAIAEEIC EQAVVHGFSA DLHCISESDK YDLKTETAPL VVVVSTTGTG DPPDTARKFV KEIQNQTLPV DFFAHLRYGL LGLGDSEYTY FCNGGKIIDK RLQELGARHF YDTGHADDCV GLELVVEPWI AGLWPALRKH FRSSRGQEEI SGALPVASPA SSRTDLVKSE LLHIESQVEL LRFDDSGRKD SEVLKQNAVN SNQSNVVIED FESSLTRSVP PLSQASLNIP GLPPEYLQVH LQESLGQEES QVSVTSADPV FQVPISKAVQ LTTNDAIKTT LLVELDISNT DFSYQPGDAF SVICPNSDSE VQSLLQRLQL EDKREHCVLL KIKADTKKKG ATLPQHIPAG CSLQFIFTWC LEIRAIPKKA FLRALVDYTS DSAEKRRLQE LCSKQGAADY SRFVRDACAC LLDLLLAFPS CQPPLSLLLE HLPKLQPRPY SCASSSLFHP GKLHFVFNIV EFLSTATTEV LRKGVCTGWL ALLVASVLQP NIHASHEDSG KALAPKISIS PRTTNSFHLP DDPSIPIIMV GPGTGIAPFI GFLQHREKLQ EQHPDGNFGA MWLFFGCRHK DRDYLFRKEL RHFLKHGILT HLKVSFSRDA PVGEEEAPAK YVQDNIQLHG QQVARILLQE NGHIYVCGDA KNMAKDVHDA LVQIISKEVG VEKLEAMKTL ATLKEEKRYL QDIWS
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MTRR Protein
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5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-110) protein (GST tag)
MTRR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-696) protein (Strep Tag)Crystallography grade MTRR Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-725) protein (His tag)Crystallography grade MTRR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-725), (full length) protein (GST tag)MTRR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-725), (full length) protein (His tag)MTRR Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
- Alternative Name
- MTRR (MTRR Products)
- Synonyms
- MSR Protein, 4732420G08 Protein, cblE Protein, MTRR Protein, 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Protein, Mtrr Protein, MTRR Protein, mtrr Protein
- Background
- Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects.
- Molecular Weight
- 107.76 kDa
- UniProt
- Q9UBK8
- Pathways
- Methionine Biosynthetic Process
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