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SKAP1 Protein (AA 1-358) (His-SUMO Tag)

SKAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4976232
  • Target See all SKAP1 Proteins
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-358
    Origin
    • 5
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SKAP1 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MQAAALPEEI RWLLEDAEEF LAEGLRNENL SAVARDHRDH ILRGFQQIKA RYYWDFQPQG GDIGQDSSDD NHSGTLGLSL TSDAPFLSDY QDEGMEDIVK GAQELDNVIK QGYLEKKSKD HSFFGSEWQK RWCVVSRGLF YYYANEKSKQ PKGTFLIKGY GVRMAPHLRR DSKKESCFEL TSQDRRSYEF TATSPAEARD WVDQISFLLK DLSSLTIPYE EDEEEEEKEE TYDDIDGFDS PSCGSQCRPT ILPGSVGIKE PTEEKEEEDI YEVLPDEEHD LEEDESGTRR KGDYASYYQG LWDCHGDQPD ELSFQRGDLI RILSKEYNMY GWWVGELNSL VGIVPKEYLT TAFEVEER
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product SKAP1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
    Alternative Name
    SKAP1 (SKAP1 Products)
    Synonyms
    1700091G21Rik Protein, Scap1 Protein, Skap-55 Protein, SCAP1 Protein, SKAP55 Protein, Skap55 Protein, src family associated phosphoprotein 1 Protein, src kinase associated phosphoprotein 1 Protein, Skap1 Protein, SKAP1 Protein
    Background
    Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
    Molecular Weight
    57.3 kDa
    UniProt
    Q86WV1
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