SKAP1 Protein (AA 1-358) (His-SUMO Tag)
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- Target See all SKAP1 Proteins
- SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-358
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SKAP1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MQAAALPEEI RWLLEDAEEF LAEGLRNENL SAVARDHRDH ILRGFQQIKA RYYWDFQPQG GDIGQDSSDD NHSGTLGLSL TSDAPFLSDY QDEGMEDIVK GAQELDNVIK QGYLEKKSKD HSFFGSEWQK RWCVVSRGLF YYYANEKSKQ PKGTFLIKGY GVRMAPHLRR DSKKESCFEL TSQDRRSYEF TATSPAEARD WVDQISFLLK DLSSLTIPYE EDEEEEEKEE TYDDIDGFDS PSCGSQCRPT ILPGSVGIKE PTEEKEEEDI YEVLPDEEHD LEEDESGTRR KGDYASYYQG LWDCHGDQPD ELSFQRGDLI RILSKEYNMY GWWVGELNSL VGIVPKEYLT TAFEVEER
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SKAP1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))
- Alternative Name
- SKAP1 (SKAP1 Products)
- Synonyms
- 1700091G21Rik Protein, Scap1 Protein, Skap-55 Protein, SCAP1 Protein, SKAP55 Protein, Skap55 Protein, src family associated phosphoprotein 1 Protein, src kinase associated phosphoprotein 1 Protein, Skap1 Protein, SKAP1 Protein
- Background
- Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
- Molecular Weight
- 57.3 kDa
- UniProt
- Q86WV1
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