BRMS1 Protein (AA 1-235, partial) (GST tag)
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- Target See all BRMS1 Proteins
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-235, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BRMS1 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product BRMS1 Protein
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Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) protein (GST tag)
BRMS1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) protein (Strep Tag)Crystallography grade BRMS1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) protein (Strep Tag)Crystallography grade BRMS1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-235), (partial) protein (GST tag)BRMS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Breast Cancer Metastasis Suppressor 1 (BRMS1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BRMS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) protein (T7 tag)BRMS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- Alternative Name
- BRMS1 (BRMS1 Products)
- Synonyms
- MGC98869 Protein, BRMS1 Protein, BRMS1L Protein, AV003220 Protein, AW554636 Protein, si:zc188c22.3 Protein, si:zc194c5.2 Protein, wu:fb57b08 Protein, zgc:56414 Protein, breast cancer metastasis suppressor 1 Protein, breast cancer metastasis-suppressor 1 Protein, breast cancer metastasis suppressor 1 L homeolog Protein, BRMS1 Protein, Brms1 Protein, brms1.L Protein, brms1 Protein
- Background
- Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
- Molecular Weight
- 54.7 kDa
- UniProt
- Q9HCU9
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