PICK1 Protein (AA 1-200, partial) (GST tag)
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- Target See all PICK1 Proteins
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 1-200
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PICK1 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MFADLDYDIE EDKLGIPTVP GKVTLQKDAQ NLIGISIGGG AQYCPCLYIV QVFDNTPAAL DGTVAAGDEI TGVNGRSIKG KTKVEVAKMI QEVKGEVTIH YNKLQADPKQ GMSLDIVLKK VKHRLVENMS SGTADALGLS RAILCNDGLV KRLEELERTA ELYKGMTEHT KNLLRAFYEL SQTHRAFGDV FSVIGVREPQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PICK1 Protein
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Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-415) protein (GST tag)
PICK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 266-375) protein (GST tag)PICK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-415) protein (Strep Tag)Crystallography grade PICK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-416) protein (Strep Tag)Crystallography grade PICK1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (AA 1-200), (partial) protein (GST tag)PICK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) proteinPICK1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PICK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Alternative Name
- PICK1 (PICK1 Products)
- Synonyms
- PICK Protein, PRKCABP Protein, Prkcabp Protein, prkcabp Protein, MGC131295 Protein, PICK1 Protein, DKFZp470L2127 Protein, protein interacting with PRKCA 1 Protein, protein interacting with C kinase 1 Protein, protein interacting with PRKCA 1 L homeolog Protein, PICK1 Protein, Pick1 Protein, pick1 Protein, pick1.L Protein
- Background
- Probable adapter protein that bind to and organize the subcellular localization of a variety of mbrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
- Molecular Weight
- 49.3 kDa
- UniProt
- Q9NRD5
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