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HDAC7 Protein (AA 1-164, partial) (His tag)

HDAC7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4976400
  • Target See all HDAC7 Proteins
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-164, partial
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HDAC7 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    PGADGTQVSP GAHYCSPTGA GCPRPCADTP GPQPQPMDLR VGQRPPVEPP PEPTLLALQR PQRLHHHLFL AGLQQQRSVE PMRLSMDTPM PELQVGPQEQ ELRQLLHKDK SKRSAVASSV VKQKLAEVIL KKQQAALERT VHPNSPGIPY RTLEPLETEG ATRSMLSSFL PPVPSLPSDP PEHFPLRKTV SEPNLKLRYK
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product HDAC7 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    Alternative Name
    HDAC7 (HDAC7 Products)
    Synonyms
    HD7A Protein, HDAC7A Protein, 5830434K02Rik Protein, HD7 Protein, HD7a Protein, Hdac7a Protein, mFLJ00062 Protein, hdac7a Protein, K2K18.5 Protein, K2K18_5 Protein, histone deacetylase7 Protein, histone deacetylase 7 Protein, histone deacetylase7 Protein, HDAC7 Protein, Hdac7 Protein, hdac7 Protein, HDA7 Protein
    Background
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors . May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 .
    Molecular Weight
    26.1 kDa
    UniProt
    Q8WUI4
    Pathways
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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