IL29 Protein (AA 21-200, partial) (His-SUMO Tag)
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- Target See all IL29 Proteins
- IL29 (Interleukin 29 (IL29))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-200, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL29 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- VPTSKPTTTG KGCHIGRFKS LSPQELASFK KARDALEESL KLKNWSCSSP VFPGNWDLRL LQVRERPVAL EAELALTLKV LEAAAGPALE DVLDQPLHTL HHILSQLQAC IQPQPTAGPR PRGRLHHWLH RLQEAPKKES AGCLEASVTF NLFRLLTRDL KYVADGNLCL RTSTHPEST-
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product IL29 Protein
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Interleukin 29 (IL29) (AA 22-200) protein (His tag)
IL29 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 29 (IL29) (AA 20-200) protein (His tag)Crystallography grade IL29 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- IL29 (Interleukin 29 (IL29))
- Alternative Name
- IFNL1 (IL29 Products)
- Synonyms
- IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
- Background
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Molecular Weight
- 35.85 kDa
- UniProt
- Q8IU54
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