FAIM3 Protein (AA 18-262, Extracellular) (His-SUMO Tag)
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- Target See all FAIM3 Proteins
- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 18-262
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FAIM3 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- RVLPEVQLNV EWGGSIIIEC PLPQLHVRMY LCRQMAKPGI CSTVVSNTFV KKEYERRVTL TPCLDKKLFL VEMTQLTEND DGIYACGVGM KTDKGKTQKI TLNVHNEYPE PFWEDEWTSE RPRWLHRFLQ HQMPWLHGSE HPSSSGVIAK VTTPAPKTEA PPVHQPSSIT SVTQHPRVYR AFSVSATKSP ALLPATTASK TSTQQAIRPL EASYSHHTRL HEQRTRHHGP HYGREDRGLH IPIPE
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product FAIM3 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
- Alternative Name
- FAIM3 (FAIM3 Products)
- Synonyms
- FAIM3 Protein, FCMR Protein, TOSO Protein, 1810037B05Rik Protein, FcmuR Protein, Toso Protein, Fc fragment of IgM receptor Protein, FCMR Protein, Fcmr Protein
- Background
- May play a role in the immune syst processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Ses to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation .
- Molecular Weight
- 43.9 kDa
- UniProt
- A1KXC4
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