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GLRa2 Protein (AA 27-143, Extracellular) (His tag)

GLRa2 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN4976729
  • Target See all GLRa2 Proteins
    GLRa2 (Glycine Receptor, alpha 2 (GLRa2))
    Protein Type
    Recombinant
    Protein Characteristics
    Extracellular, AA 27-143
    Origin
    • 4
    • 4
    • 1
    Mouse
    Source
    • 4
    • 2
    • 2
    • 1
    Yeast
    Purification tag / Conjugate
    This GLRa2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product GLRa2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    GLRa2 (Glycine Receptor, alpha 2 (GLRa2))
    Alternative Name
    GLR (GLRa2 Products)
    Synonyms
    GLR Protein, RNNEOGLY Protein, glycine receptor alpha 2 Protein, glycine receptor, alpha 2 Protein, glycine receptor, alpha 2 subunit Protein, GLRA2 Protein, Glra2 Protein, glra2 Protein
    Background
    G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger syst.
    Molecular Weight
    15.8 kDa
    UniProt
    Q61606
    Pathways
    Synaptic Membrane
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