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CENPA Protein (AA 1-134, full length) (His tag)

CENPA Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN4976752
  • Target See all CENPA Proteins
    CENPA (Centromere Protein A (CENPA))
    Protein Type
    Recombinant
    Protein Characteristics
    full length, AA 1-134
    Origin
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 7
    • 2
    • 2
    • 1
    Yeast
    Purification tag / Conjugate
    This CENPA protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGPRRKPQTP RRRPSSPAPG PSRQSSSVGS QTLRRRQKFM WLKEIKTLQK STDLLFRKKP FSMVVREICE KFSRGVDFWW QAQALLALQE AAEAFLIHLF EDAYLLSLHA GRVTLFPKDI QLTRRIRGFE GGLP
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product CENPA Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CENPA (Centromere Protein A (CENPA))
    Alternative Name
    CENPA (CENPA Products)
    Synonyms
    CENP-A Protein, CenH3 Protein, Cenp-A Protein, cenpx Protein, cenp-a Protein, sim2 Protein, Cenp-a Protein, RGD1563607 Protein, CENPA Protein, centromere protein A Protein, centromere protein-A Protein, centromeric histone-3 like protein Protein, centromere-specific histone H3 CENP-A Protein, cenp-A Protein, centromere protein A L homeolog Protein, histone H3-like centromeric protein A Protein, CENPA Protein, Cenpa Protein, CENP-A Protein, cenpa Protein, cenp-A Protein, cnp1 Protein, HAN_3g422 Protein, Cenp-a Protein, cenpa.L Protein, CMU_016480 Protein
    Background
    Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assbly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro) .
    Molecular Weight
    17.51 kDa
    UniProt
    O35216
    Pathways
    Chromatin Binding, Maintenance of Protein Location
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