SRY Protein (AA 1-144, partial) (His tag)
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- Target See all SRY Proteins
- SRY (Sex Determining Region Y (SRY))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-144, partial
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SRY protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE KRPFFQEAQR LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SRY Protein
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Sex Determining Region Y (SRY) (AA 1-204) protein (GST tag)
SRY Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Sex Determining Region Y (SRY) (AA 1-395) protein (His tag)Crystallography grade SRY Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Sex Determining Region Y (SRY) (AA 1-204) protein (Strep Tag)Crystallography grade SRY Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Sex Determining Region Y (SRY) (AA 1-144), (partial) protein (His tag)SRY Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- SRY (Sex Determining Region Y (SRY))
- Alternative Name
- SRY (SRY Products)
- Synonyms
- SRXX1 Protein, SRXY1 Protein, TDF Protein, TDY Protein, SRYGENE Protein, Sry1 Protein, Sry3BI Protein, Tdf Protein, Tdy Protein, SRY Protein, sex determining region Y Protein, sex determining region of Chr Y Protein, SRY Protein, Sry Protein
- Background
- Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons . Involved in different aspects of gene regulation including promoter activation or repression. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending. Also involved in pre-mRNA splicing . Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.1 Publication
- Molecular Weight
- 21.3 kDa
- UniProt
- Q05738
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