ARHGAP8 Protein (His tag)

Catalog No. ABIN5505761

Product Details

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ARHGAP8 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Purified recombinant protein of Human Rho GTPase activating protein 8 (ARHGAP8), transcript variant 1 , full length, with N-terminal HIS tag, expressed in E.coli, 50 μg (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Alternative Name: Rho GTPase activating protein 8 (ARHGAP8 Products)

Synonyms: BPGAP1 Protein, PP610 Protein, 3110043J09Rik Protein, AU043908 Protein, Arhgap8 Protein, C030017C09Rik Protein, C78947 Protein, Protor-1 Protein, Protor1 Protein, Rho GTPase activating protein 8 Protein, proline rich 5 (renal) Protein, proline rich 5 Protein, ARHGAP8 Protein, Arhgap8 Protein, arhgap8 Protein, Prr5 Protein

Background: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Molecular Weight: 53.3 kDa

NCBI Accession: NP_001017526