Leptin Receptor (LEPR) (Active) Protein

Name: Leptin Receptor (LEPR)

Synonyms: OBR, CD295, obr, cd295, ob-rb

Protein Type: Recombinant

Biological Activity: Active

Source: Escherichia Coli (E. coli)

Origin (Gene): Human

Catalog no.: ABIN593498

Additional Information

Gene ID: 3952

UniProt: P41159

Sequence: The sequence of the first four N-terminal amino acids was determined and was found to be Ala-Thr-Pro-Val

Description: Leptin Binding Domain Human Recombinant also called Leptin soluble receptor produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids and having a molecular mass of 24.5 kDa. Leptin Receptor consists of the cytokine binding domain of leptin receptor amino acids 428-635 of human leptin receptor. The Leptin Binding Domain is purified by proprietary chromatographic techniques.
Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor, recombinant leptin receptor, human leptin, human leptin receptor, recombinant human leptin receptor,,

Characteristics: Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.

Specificity: Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.

Molecular Weight: 24.5 kDa

Application Details

Handling Advice: Centrifuge the vial prior to opening.

Purity: SDS-PAGE: >=98%, HPLC: >=98%

Buffer: Lyophilized from 0.0045 mM NaHCO3

Storage: -20°C.
Stability: 12 months

Research Area: Diabetes, Cytokines, Growth Factors, Animal-Free Origin

Restrictions: For Research Use only

Publications

Product: Sato, Schehr, Ikegami: "Leptin does not influence surfactant synthesis in fetal sheep and mice lungs." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 3, pp. L498-505, 2011 (PubMed).