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Details for Product No. ABIN593498

Leptin Receptor (LEPR) (Active) Protein

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Protein Name
Synonyms CD295, LEP-R, LEPRD, OB-R, OBR, LEPR, OB-RGRP, Obrgrp, VPS55, Fa, LEPROT, Leprb, Modb1, Obr, db, diabetes, obese-like, obl, ObRb, Ob-R, Ob-RM, obr, cd295, ob-rb
Origin
»Alternatives Human
Source
»Alternatives Escherichia coli (E. coli)
Protein Type Recombinant
Biological Activity Active
Pubmed 1 reference available
Catalog no. ABIN593498
Quantity 1 mg
Price
5,445.00 $   Plus shipping costs $45.00
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Sequence Ala-Thr-Pro-Val
Specificity Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
Characteristics Biological activity: Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
Purity SDS-PAGE: ≥ 98 %, HPLC: ≥ 98 %
Alternative Name Leptin Receptor
Background Leptin Binding Domain Human Recombinant also called Leptin soluble receptor produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids and having a molecular mass of 24.5 kDa. Leptin Receptor consists of the cytokine binding domain of leptin receptor amino acids 428-635 of human leptin receptor. The Leptin Binding Domain is purified by proprietary chromatographic techniques.
Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor, recombinant leptin receptor, human leptin, human leptin receptor, recombinant human leptin receptor,
Molecular Weight 24.5 kDa
Gene ID 3952
UniProt P41159
Research Area Cardiovascular, Fatty Acids, Hormones, Receptors, Diabetes, Cytokines, Growth Factors, Animal-Free Origin
Restrictions For Research Use only
Format Lyophilized
Reconstitution The lyophilized Leptin Binding Domain is very soluble in H2O and most aqueous buffers below and above the isoelectric point (approx. 5.9).
Buffer 0.0045 mM NaHCO3
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Product cited in: Sato, Schehr, Ikegami: "Leptin does not influence surfactant synthesis in fetal sheep and mice lungs." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 300, Issue 3, pp. L498-505, 2011 (PubMed).

Alternatives for antigen "Leptin Receptor (LEPR)", type "Proteins"
Hosts (9), (3), (3)
Reactivities (15), (5), (1), (1)
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