Uroplakin 3A Protein (UPK3A) (AA 19-207) (His tag)
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- Target See all Uroplakin 3A (UPK3A) Proteins
- Uroplakin 3A (UPK3A)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-207
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Uroplakin 3A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- UPK3A, 19-207aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product UPK3A Protein
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Uroplakin 3A (UPK3A) (AA 19-207) protein (His tag)
UPK3A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Uroplakin 3A (UPK3A) (AA 19-287) protein (rho-1D4 tag)Crystallography grade UPK3A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
- Storage
- 4 °C
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- Target
- Uroplakin 3A (UPK3A)
- Alternative Name
- UPK3A (UPK3A Products)
- Synonyms
- UP3A Protein, UPIII Protein, UPIIIA Protein, UPK3 Protein, upk3 Protein, upiii Protein, MGC75921 Protein, 1110017C07Rik Protein, UP3a Protein, Upk3 Protein, up3a Protein, upiiia Protein, upk3a Protein, xUPIII Protein, uroplakin 3A Protein, uroplakin 3 Protein, uroplakin 3A L homeolog Protein, UPK3A Protein, upk3a Protein, Upk3a Protein, LOC100008738 Protein, upk3a.L Protein
- Background
- UPK3A belongs to the uroplakin-3 family. Uroplakins (UP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (UPII, UPIIIa, and UPIIIb) or four times (UPIa and UPIb, both belonging to the 'tetraspanin' family). All have large luminal/extracellular domains, but only UPIIIa and UPIIIb have significant cytoplasmic portions in their C-termini. UPK3A is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Mutations in this gene may be associated with renal adysplasia Recombinant human UPK3A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Uroplakin-3a, UPK3. NCBI no.: BAA31460
- Molecular Weight
- 23.1kDa (214aa), confirmed by MALDI-TOF
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