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AES Protein (AA 1-197) (His tag)

AES Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666634
  • Target See all AES Proteins
    AES (Amino-terminal Enhancer of Split (AES))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-197
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This AES protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    AES, 1-197aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product AES Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
    Storage
    4 °C
  • Target
    AES (Amino-terminal Enhancer of Split (AES))
    Alternative Name
    AES (AES Products)
    Synonyms
    AES-1 Protein, AES-2 Protein, ESP1 Protein, GRG Protein, GRG5 Protein, TLE5 Protein, AL024115 Protein, Esp1 Protein, Grg Protein, Grg-5 Protein, Grg5 Protein, Tle5 Protein, zgc:64216 Protein, aes-1 Protein, aes-2 Protein, esp1 Protein, grg Protein, grg5 Protein, tle5 Protein, xgrg-5 Protein, AES Protein, amino-terminal enhancer of split Protein, amino-terminal enhancer of split S homeolog Protein, AES Protein, Aes Protein, aes Protein, aes.S Protein
    Background
    Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Recombinant human AES protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Amino-terminal enhancer of split, AES-1, AES-2, ESP1, GRG, GRG5, TLE5, Groucho homologue. NCBI no.: NP_001121
    Molecular Weight
    24.1 kDa (217aa) confirmed by MALDI-TOF
    Pathways
    WNT Signaling, SARS-CoV-2 Protein Interactome
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