AES Protein (AA 1-197) (His tag)
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- Target See all AES Proteins
- AES (Amino-terminal Enhancer of Split (AES))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-197
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AES protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- AES, 1-197aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product AES Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- AES (Amino-terminal Enhancer of Split (AES))
- Alternative Name
- AES (AES Products)
- Synonyms
- AES-1 Protein, AES-2 Protein, ESP1 Protein, GRG Protein, GRG5 Protein, TLE5 Protein, AL024115 Protein, Esp1 Protein, Grg Protein, Grg-5 Protein, Grg5 Protein, Tle5 Protein, zgc:64216 Protein, aes-1 Protein, aes-2 Protein, esp1 Protein, grg Protein, grg5 Protein, tle5 Protein, xgrg-5 Protein, AES Protein, amino-terminal enhancer of split Protein, amino-terminal enhancer of split S homeolog Protein, AES Protein, Aes Protein, aes Protein, aes.S Protein
- Background
- Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Recombinant human AES protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Amino-terminal enhancer of split, AES-1, AES-2, ESP1, GRG, GRG5, TLE5, Groucho homologue. NCBI no.: NP_001121
- Molecular Weight
- 24.1 kDa (217aa) confirmed by MALDI-TOF
- Pathways
- WNT Signaling, SARS-CoV-2 Protein Interactome
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