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PTTG1 Protein (AA 1-202) (His tag)

PTTG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
Catalog No. ABIN666649
  • Target See all PTTG1 Proteins
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-202
    Origin
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PTTG1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PTTG1, 1-202 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 80 % by SDS - PAGE
    Top Product
    Discover our top product PTTG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 10% glycerol
    Storage
    4 °C
  • Target
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    Alternative Name
    PTTG1 (PTTG1 Products)
    Synonyms
    EAP1 Protein, HPTTG Protein, PTTG Protein, TUTR1 Protein, PTTG1 Protein, securin Protein, AW555095 Protein, C87862 Protein, Pttg Protein, Pttg3 Protein, Securin Protein, Protein Cut2 Protein, pituitary tumor-transforming 1 Protein, pituitary tumor-transforming gene 1 Protein, securin, sister chromatid separation inhibitor Protein, PTTG1 Protein, Pttg1 Protein, cut2 Protein
    Background
    PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles, the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EAP1, HPTTG, PTTG, TUTR1, SECURIN, Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1, Esp1-associated protein, MGC126883, MGC138276, Pds1, PTTG1 protein, PTTG1, Pituitary tumor transforming 1, PTTG 1, EAP 1, Cut2, Pituitary tumor transforming protein 1, AW555095, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor-transforming 1, isoform CRA_b, hPTTG, Pituitary tumor-transforming gene 1, TUTR 1, Pttg3, Pituitary tumor-transforming gene 1 protein, C87862, TUMOR TRANSFORMING 1, Tumor transforming protein 1,. NCBI no.: NP_004210
    Molecular Weight
    24.1 kDa (222aa), confirmed by MALDI-TOF.
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