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PTP4A3 Protein (AA 1-173) (His tag)

PTP4A3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666667
  • Target See all PTP4A3 Proteins
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-173
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PTP4A3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PRL-3, 1-173 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PTP4A3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 2 mM EDTA, 1 mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Alternative Name
    PRL-3 (PTP4A3 Products)
    Synonyms
    PRL-3 Protein, PRL-R Protein, PRL3 Protein, wu:fc54b05 Protein, wu:fv52d11 Protein, zgc:77109 Protein, prl-3 Protein, prl3 Protein, ptpcaax3 Protein, PTP4A3 Protein, AV088979 Protein, Prl-3 Protein, pPtp4a3 Protein, protein tyrosine phosphatase type IVA, member 3 Protein, protein tyrosine phosphatase type IVA, member 3 L homeolog Protein, protein tyrosine phosphatase 4a3 Protein, PTP4A3 Protein, ptp4a3 Protein, ptp4a3.L Protein, Ptp4a3 Protein
    Background
    Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. Recombinant human PRL-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PTP4A3, PRL3, Protein tyrosine phosphatase type IVA 3 Potentially prenylated protein tyrosine phosphatase, PRL 3, PRL R, PRLR, Protein tyrosine phosphatase 4a3, PTP 4A3, Protein Tyrosine Phosphatase Type IVA Member 3. NCBI no.: NP_116000
    Molecular Weight
    21.6 kDa (193aa), confirmed by MALDI-TOF.
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