GNMT Protein (AA 1-295) (His tag)
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- Target See all GNMT Proteins
- GNMT (Glycine N-Methyltransferase (GNMT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-295
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GNMT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GNMT, 1-295aa, Human,His-Tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GNMT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in 20mM Tris pH 8.0, 20% glycerol
- Storage
- 4 °C
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- Target
- GNMT (Glycine N-Methyltransferase (GNMT))
- Alternative Name
- GNMT (GNMT Products)
- Background
- Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). Recombinant human GNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GNMT, Glycine N-methyltransferase, Glycine N-methyltransferase EC 2.1.1.20, Glycine N methyltransferase. NCBI no.: NP_061833
- Molecular Weight
- 34.9kDa (315aa), confirmed by MALDI-TOF.
- Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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