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CCL2 Protein (AA 24-99) (His tag)

CCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666739
  • Target See all CCL2 Proteins
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-99
    Origin
    • 23
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 34
    • 12
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CCL2/MCP-1, 24-99 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CCL2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 20% glycerol
    Storage
    4 °C
  • Target
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Alternative Name
    CCL2/MCP-1 (CCL2 Products)
    Synonyms
    GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein
    Background
    Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant human CCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MCAF, GDCF-2, HC11, SCYA2, Chemokine (C-C motif) ligand 2, CCL2, small inducible cytokine A2 (monocyte chemotactic protein 1 homologous to mouse Sig-je), MCP1, MCP-1, SMC-CF, MGC9434,. NCBI no.: NP_002973
    Molecular Weight
    10.9 kDa (97 aa), confirmed by MALDI-TOF.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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