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GDF5 Protein (AA 382-501) (His tag)

GDF5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666773
  • Target See all GDF5 Proteins
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 382-501
    Origin
    • 9
    • 4
    • 2
    Human
    Source
    • 12
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GDF5 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    GDF-5, 382-501aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GDF5 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 10 mM Sodium citrate pH 3.5, 10% glycerol
    Storage
    4 °C
  • Target
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Alternative Name
    GDF-5 (GDF5 Products)
    Synonyms
    CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
    Background
    Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Growth differentiation factor 5, BMP14, CDMP1, LAP4, OS5, SYNS2, Growth differentiation factor 5 Cartilage derived morphogenetic protein 1,. NCBI no.: NP_000548
    Molecular Weight
    15.8 kDa (141aa), confirmed by MALDI-TOF.
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