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CCL3 Protein (AA 24-92) (His tag)

CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666794
  • Target See all CCL3 Proteins
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-92
    Origin
    • 19
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 22
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CCL3, 24-92aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CCL3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 10mM Sodium Citrate ( pH3.5) containing 10% glycerol
    Storage
    4 °C
  • Target
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Alternative Name
    CCL3 (CCL3 Products)
    Synonyms
    MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
    Background
    CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner. Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: C-C motif chemokine 3, G0S19-1, LD78ALPHA. MIP-1-alpha. MIP1A. SCYA3. NCBI no.: NP_002974
    Molecular Weight
    10.0 kDa (90aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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