NDRG1 Protein (AA 1-394) (His tag)

Catalog No. ABIN666891

Product Details

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Protein Type: Recombinant

Protein Characteristics: AA 1-394

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NDRG1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: NDRG1, 1-394 aa, Human, His-tagged, Recombinant, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1 mM PMSF, 10% Glycerol

Storage: 4 °C

Target Details

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1 (NDRG1 Products)

Synonyms: CAP43 Protein, CMT4D Protein, DRG-1 Protein, DRG1 Protein, GC4 Protein, HMSNL Protein, NDR1 Protein, NMSL Protein, PROXY1 Protein, RIT42 Protein, RTP Protein, TARG1 Protein, TDD5 Protein, Ndr1 Protein, Ndrl Protein, cap43 Protein, cmt4d Protein, drg1 Protein, gc4 Protein, hmsnl Protein, ndr1 Protein, ndrg1 Protein, nmsl Protein, proxy1 Protein, rit42 Protein, rtp Protein, targ1 Protein, tdd5 Protein, xndrg1 Protein, ndrg4 Protein, cb775 Protein, wu:fb60h02 Protein, zgc:63944 Protein, NDRG1 Protein, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN Protein, non race-specific disease resistance 1 Protein, ndrg1-a Protein, ndrg1-b Protein, xNDRG1-A Protein, ndrg1l Protein, zgc:73047 Protein, N-myc downstream regulated 1 Protein, N-myc downstream regulated gene 1 Protein, N-myc downstream regulated 1 S homeolog Protein, N-myc downstream regulated 1a Protein, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Protein, N-myc downstream regulated 1 L homeolog Protein, N-myc downstream regulated 1b Protein, NDRG1 Protein, Ndrg1 Protein, ndrg1.S Protein, ndrg1 Protein, ndrg1a Protein, NDR1 Protein, ndrg1.L Protein, ndrg1b Protein

Background: N-myc downstream regulated gene (NDRG)-1 is one of 4 members of the NDRG alpha/beta-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease. Recombinant human NDRG1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 TDD5, 42 kDa, anti-GC4, cmt4d, Differentiation related gene1 protein, Drg 1, hmsnl, Human mRNA for RTP complete cds, NDRG1, tdds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, NDRG1 protein, Protein nickel specific induction protein, Nickel specific induction protein Cap43, nmsl, Nmyc downstream regulated, reduced in tumor, reducin, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein regulated by oxygen 1, Protein regulated by oxygen1, proxy1, Reducing agents and tunicamycin responsive protein, tunicamycin-responsive protein. NCBI no.: NP_006087

Molecular Weight: 43.9 kDa (402aa), confirmed by MALDI-TOF.