TCL1A Protein (AA 1-114)
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- Target See all TCL1A Proteins
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-114
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- TCL1A, 1-114 aa, Human, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TCL1A Protein
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T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-114) protein (GST tag)
TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 61-114) protein (GST tag)TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 7-102) protein (GST tag)TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-116) protein (Strep Tag)Crystallography grade TCL1A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
T-Cell Leukemia/lymphoma 1A (TCL1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
T-Cell Leukemia/lymphoma 1A (TCL1A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 50mM Tris-HCl buffer (pH7.5) containing 10% glycerol
- Storage
- 4 °C
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- Target
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Alternative Name
- TCL1A (TCL1A Products)
- Synonyms
- TCL1A Protein, Tcl1a Protein, TCL1 Protein, Tcl1 Protein, T-cell leukemia/lymphoma 1A Protein, T cell lymphoma breakpoint 1 Protein, TCL1A Protein, Tcl1 Protein, Tcl1a Protein
- Background
- TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A. NCBI no.: NP_001092195
- Molecular Weight
- 13.4 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Stem Cell Maintenance
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