GSTM1 Protein (AA 1-218) (His tag)

Catalog No. ABIN666904

Product Details

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Protein Type: Recombinant

Protein Characteristics: AA 1-218

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GSTM1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: Glutathione S-Transferase Mu1, 1-218 aa, Mouse, His-tag, E.coli

Purity: > 95 % by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer ( pH8.0) containing 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Alternative Name: Glutathione S-Transferase Mu1 (GSTM1 Products)

Synonyms: GST1 Protein, GSTM1-1 Protein, GSTM1a-1a Protein, GSTM1b-1b Protein, GTH4 Protein, GTM1 Protein, H-B Protein, MU Protein, MU-1 Protein, GSTA3 Protein, Gstb-1 Protein, Gstb1 Protein, gst-mu Protein, gst1 Protein, gstm1 Protein, gstm2 Protein, gth4 Protein, gtm1 Protein, glutathione S-transferase mu 1 Protein, glutathione S-transferase M1 Protein, glutathione S-transferase, mu 1 Protein, glutathione S-transferase Mu 1 Protein, glutathione S-transferase mu 2 (muscle) Protein, glutathione S-transferase mu 1 L homeolog Protein, GSTM1 Protein, Gstm1 Protein, LOC100356307 Protein, GSTM2 Protein, LOC100731426 Protein, gstm1.L Protein

Background: GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. Recombinant GSTM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GSTM1, GST class-mu1, GST 1-1, pmGT10, Glutathione S transferase mu, GST class Mu, GST class mu 1, GST mu, GST1, Glutathione S-Transferase Mu 1. NCBI no.: NP_034488

Molecular Weight: 28.1 kDa (238aa), confirmed by MALDI-TOF.

Pathways: Negative Regulation of Transporter Activity