Alcohol Dehydrogenase (ADH) (AA 1-325) Protein

Catalog No. ABIN666916

Product Details

Target: Alcohol Dehydrogenase (ADH)

Protein Type: Recombinant

Protein Characteristics: AA 1-325

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Characteristics: Alcohol dehydrogenase, 1-325aa, Human, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 50mM NaCl, 10% glycerol

Storage: 4 °C

Target Details

Target: Alcohol Dehydrogenase (ADH)

Alternative Name: Alcohol dehydrogenase (ADH Products)

Synonyms: ADH Protein, ALCOHOL DEHYDROGENASE Protein, ARABIDOPSIS THALIANA ALCOHOL DEHYDROGENASE Protein, ATADH Protein, ATADH1 Protein, F22K20.19 Protein, F22K20_19 Protein, alcohol dehydrogenase 1 Protein, 2610201A18Rik Protein, Akr1a4 Protein, ALR1 Protein, Adh Protein, Adh1a Protein, Adh1c Protein, aldo-keto reductase family 1 member A1 Protein, alcohol dehydrogenase 1 Protein, aldo-keto reductase family 1, member A1 (aldehyde reductase) Protein, alcohol dehydrogenase 1 (class I) Protein, AKR1A1 Protein, ADH1 Protein, Akr1a1 Protein, Adh1 Protein

Background: Alcohol dehydrogenase [NADP+] (AKR1A1) is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65% identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Recombinant human Alcohol dehydrogenase was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AKR1A1, ALDR1, ALR, ARM, DD3, Alcohol dehydrogenase [NADP+] Alcohol dehydrogenase, Aldehyde reductase, aldo-keto reductase family 1 member A1 (aldehyde reductase). NCBI no.: NP_006057

Molecular Weight: 36.5 kDa (325aa), confirmed by MALDI-TOF.