CAPG Protein (AA 1-348)
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- Target See all CAPG Proteins
- CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-348
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- CAPG, 1-348aa, Human, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CAPG Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))
- Alternative Name
- CAPG (CAPG Products)
- Synonyms
- AFCP Protein, MCP Protein, gCap39 Protein, mbh1 Protein, capping actin protein, gelsolin like Protein, capping protein (actin filament), gelsolin-like Protein, CAPG Protein, Capg Protein
- Background
- Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MCP, AFCP, Macrophage-capping protein Actin capping protein GCAP39, Actin regulatory protein CAP G, CAPG, Capping protein (actin filament) gelsolin like, Capping protein gelsolin like, gCap39, Gelsolin like capping protein, Macrophage capping protein, mbh1, Myc basic motif homolog 1. NCBI no.: AAH00728
- Molecular Weight
- 38.5 kDa (348aa), confirmed by MALDI-TOF.
- Pathways
- Regulation of Actin Filament Polymerization
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