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CAPG Protein (AA 1-348)

CAPG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666921
  • Target See all CAPG Proteins
    CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-348
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Characteristics
    CAPG, 1-348aa, Human, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CAPG Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))
    Alternative Name
    CAPG (CAPG Products)
    Synonyms
    AFCP Protein, MCP Protein, gCap39 Protein, mbh1 Protein, capping actin protein, gelsolin like Protein, capping protein (actin filament), gelsolin-like Protein, CAPG Protein, Capg Protein
    Background
    Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MCP, AFCP, Macrophage-capping protein Actin capping protein GCAP39, Actin regulatory protein CAP G, CAPG, Capping protein (actin filament) gelsolin like, Capping protein gelsolin like, gCap39, Gelsolin like capping protein, Macrophage capping protein, mbh1, Myc basic motif homolog 1. NCBI no.: AAH00728
    Molecular Weight
    38.5 kDa (348aa), confirmed by MALDI-TOF.
    Pathways
    Regulation of Actin Filament Polymerization
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