MCFD2 Protein (AA 27-146) (T7 tag)

Catalog No. ABIN666930

Product Details

Target: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Protein Type: Recombinant

Protein Characteristics: AA 27-146

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MCFD2 protein is labelled with T7 tag.

Application: SDS-PAGE (SDS)

Characteristics: MCFD2, 27-146aa, Human, T7 tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol

Storage: 4 °C

Target Details

Target: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Alternative Name: MCFD2 (MCFD2 Products)

Synonyms: hm:zeh1186 Protein, wu:fc23b10 Protein, wu:fd50d08 Protein, zgc:103713 Protein, zgc:109915 Protein, MCFD2 Protein, DKFZp469B098 Protein, F5F8D Protein, F5F8D2 Protein, LMAN1IP Protein, SDNSF Protein, 1810021C21Rik Protein, F5f8d Protein, Lman1ip Protein, Sdnsf Protein, multiple coagulation factor deficiency 2 Protein, multiple coagulation factor deficiency 2 L homeolog Protein, MCFD2 Protein, mcfd2 Protein, mcfd2.L Protein, Mcfd2 Protein

Background: Multiple coagulation factor deficiency 2 (MCFD2), also known as SDNSF. This is expressed by neural stem/progenitor cells of the hippocampus, and localized to region where neurogenesis persists throughout life. It has been found to prevent NSC cell death and to maintain stem cell characteristics. This protein forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment. Mutations in the MCFD2 gene may cause Factor V and Factor VIII combined deficiency. Recombinant human MCFD2, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SDNSF, LMAN1IP, Multiple coagulation factor deficiency 2 MCFD 2, DKFZp686G21263, F5F8D, Neural stem cell derived neuronal survival protein, Multiple coagulation factor deficiency protein 2. NCBI no.: NP_644808

Molecular Weight: 15.1 kDa (136aa), confirmed by MALDI-TOF.