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IVD Protein (AA 33-426) (His tag)

IVD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666949
  • Target See all IVD Proteins
    IVD (Isovaleryl-CoA Dehydrogenase (IVD))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 33-426
    Origin
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IVD protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    IVD, 33-426aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    IVD (Isovaleryl-CoA Dehydrogenase (IVD))
    Alternative Name
    IVD (IVD Products)
    Synonyms
    1300016K07Rik Protein, 6720455E18Rik Protein, AI463340 Protein, ACAD2 Protein, ATIVD Protein, ISOVALERYL-COA-DEHYDROGENASE Protein, ISOVALERYL-COA-DEHYDROGENASE PRECURSOR Protein, IVDH Protein, isovaleryl-CoA-dehydrogenase Protein, isovaleryl coenzyme A dehydrogenase Protein, isovaleryl-CoA dehydrogenase Protein, isovaleryl-CoA-dehydrogenase Protein, Ivd Protein, IVD Protein
    Background
    IVD (Isovaleryl Coenzyme A dehydrogenase) is a mitochondrial matrix enzyme that belongs to the acyl-CoA dehydrogenase family. IVD is a homotetrameric flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects of the IVD gene lead to ineffective isoforms that are the underlying cause of isovaleric acidemia. Recombinant human IVD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ACAD2, Isovaleryl-CoA dehydrogenase, mitochondrial Isovaleryl CoA dehydrogenase, Isovaleryl CoA dehydrogenase, mitochondrial, isovaleryl Coenzyme A dehydrogenase. NCBI no.: NP_002216
    Molecular Weight
    45.3 kDa (415aa), confirmed by MALDI-TOF.
    Pathways
    Monocarboxylic Acid Catabolic Process
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