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RAB27A Protein (AA 1-221) (His tag)

RAB27A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666995
  • Target See all RAB27A Proteins
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-221
    Origin
    • 9
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RAB27A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    RAB27A, 1-221aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product RAB27A Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
    Storage
    4 °C
  • Target
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Alternative Name
    RAB27A (RAB27A Products)
    Synonyms
    MGC80943 Protein, RAB27A Protein, gs2 Protein, ram Protein, rab27 Protein, MGC89827 Protein, hst18676 Protein, zgc:114135 Protein, GS2 Protein, HsT18676 Protein, RAB27 Protein, RAM Protein, 2210402C08Rik Protein, 2410003M20Rik Protein, 4933437C11Rik Protein, ash Protein, RAB27A, member RAS oncogene family L homeolog Protein, RAB27A, member RAS oncogene family Protein, RAB27A, member RAS oncogene family S homeolog Protein, rab27a.L Protein, RAB27A Protein, rab27a Protein, rab27a.S Protein, Rab27a Protein
    Background
    Ras-related protein Rab-27A, also known as RAB27A, belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Also, RAB27A regulates the cytotoxic granule exocytosis and affect T-lymphocyte and macrophage-activation. It is widely expressed with significant expression in pancreatic islets and pituitary tissue, and low expression in brain. Defects in RAB27A cause Griscelli syndrome type 2 (GS2). Recombinant human RAB27A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GS2, RAM, RAB27, Ras-related protein Rab-27A GTP-binding protein Ram, HsT18676.MGC117246, Rab-27, RAB27A, member RAS oncogene family, Ras-related protein Rab27A. NCBI no.: NP_899059
    Molecular Weight
    27 kDa (241aa), confirmed by MALDI-TOF
    Pathways
    Peptide Hormone Metabolism
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