Fission 1 Protein (FIS1) (AA 1-122) (His tag)
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- Target See all Fission 1 (FIS1) Proteins
- Fission 1 (FIS1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-122
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Fission 1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TTC11, 1-122aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product FIS1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- Fission 1 (FIS1)
- Alternative Name
- TTC11 (FIS1 Products)
- Synonyms
- TTC11 Protein, 2010003O14Rik Protein, Ttc11 Protein, fission, mitochondrial 1 Protein, FIS1 Protein, Fis1 Protein
- Background
- TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission. Recombinant human TTC11, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: FIS1, Tetratricopeptide repeat domain 11 2010003O14Rik, CGI 135, CGI135, FIS 1, Fis1 homolog, FIS1, S, cerevisiae, homolog of, Fission 1 (mitochondrial outer membrane) homolog, Fission 1 (mitochondrial outer membrane) homolog (S, cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast) Fission 1 homolog, H NH0132A01.6, hFis 1, hFis1, Mitochondrial fission 1 protein, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11. NCBI no.: NP_057152
- Molecular Weight
- 16.3 kDa(142aa), confirmed by MALDI-TOF
- Pathways
- Positive Regulation of Endopeptidase Activity
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