FHIT Protein (AA 1-147) (His tag)
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- Target See all FHIT Proteins
- FHIT (Fragile Histidine Triad (FHIT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-147
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FHIT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- FHIT, 1-147aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product FHIT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- FHIT (Fragile Histidine Triad (FHIT))
- Alternative Name
- FHIT (FHIT Products)
- Synonyms
- AP3Aase Protein, FRA3B Protein, FHIT Protein, zgc:73176 Protein, AW045638 Protein, Fra14A2 Protein, LOC100223655 Protein, fragile histidine triad Protein, fragile histidine triad gene Protein, fragile histidine triad protein Protein, fragile histidine triad L homeolog Protein, FHIT Protein, Fhit Protein, fhit Protein, PY07476 Protein, fhit.L Protein
- Background
- FHIT (fragile histidine triad) is an enzyme that cleaves adenosine 5' PPP 5' A to yield AMP and ADP. FHIT gene encompasses the common fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. This protein physically associates with ubiquitin conjugating enzyme 9. Recombinant human FHIT, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bis (5'-adenosyl)-triphosphatase , AP3Aase, Fragile histidine triad protein AP3A hydrolase, AP3A hydrolase fragile site 3p14.2, Bis 5' adenosyl triphosphatase, Diadenosine 5' 5''' P1 P3 triphosphate hydrolase, Dinucleosidetriphosphatase, FRA 3B, FRA3B, Fragile histidine triad, Fragile histidine triad gene, Fragile histidine triad protein, Tumor suppressor protein. NCBI no.: NP_002003
- Molecular Weight
- 17.9 kDa(155aa), confirmed by MALDI-TOF
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