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CACYBP Protein (AA 1-185) (His tag)

CACYBP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS-PAGE SDS
Catalog No. ABIN667003
  • Target See all CACYBP Proteins
    CACYBP (Calcyclin Binding Protein (CACYBP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-185
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CACYBP protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CACYBP, 1-185aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS-PAGE
    Top Product
    Discover our top product CACYBP Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
    Storage
    4 °C
  • Target
    CACYBP (Calcyclin Binding Protein (CACYBP))
    Alternative Name
    CACYBP (CACYBP Products)
    Synonyms
    zgc:76993 Protein, CACYBP Protein, sip Protein, gig5 Protein, pnas-107 Protein, s100a6bp Protein, T1P2.12 Protein, T1P2_12 Protein, GIG5 Protein, RP1-102G20.6 Protein, S100A6BP Protein, SIP Protein, calcyclin binding protein Protein, calcyclin binding protein, putative Protein, Calcyclin binding protein, putative Protein, SGS domain-containing protein Protein, calcyclin binding protein L homeolog Protein, cacybp Protein, CACYBP Protein, PB000926.02.0 Protein, PCHAS_145490 Protein, PVX_100855 Protein, PKH_145680 Protein, AT1G30070 Protein, cacybp.L Protein, Cacybp Protein
    Background
    CACYBP is primarily a nuclear protein that contains one CS domain and one SGS domain. It is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in Ubiquitin E3 complexes. It also participates in the Ubiquitin-mediated degradation of beta-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on beta-catenin protein expression and transcriptional activation of TCF/LEF. Recombinant human CACYBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GIG5, PNAS-107, RP1-102G20.6, S100A6BP, SIP, Clcyclin-binding protein CACYBP, Calcyclin binding protein, GIG 5, Growth inhibiting gene 5, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein. NCBI no.: NP_001007215
    Molecular Weight
    23.4 kDa (205aa), confirmed by MALDI-TOF
    Pathways
    Response to Growth Hormone Stimulus
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