TXNRD1 Protein (AA 161-647) (His tag)
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- Target See all TXNRD1 Proteins
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 161-647
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TXNRD1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TXNRD1, 161-647aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product TXNRD1 Protein
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Thioredoxin Reductase 1 (TXNRD1) (AA 161-647) (Active) protein (His tag)
TXNRD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) protein (GST tag)TXNRD1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thioredoxin Reductase 1 (TXNRD1) (AA 2-499) protein (His tag)TXNRD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) (AA 1-649) protein (Strep Tag)Crystallography grade TXNRD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) (AA 1-613) protein (Strep Tag)Crystallography grade TXNRD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Thioredoxin Reductase 1 (TXNRD1) (AA 1-497), (partial) protein (His-SUMO Tag)TXNRD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol
- Storage
- 4 °C
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- Target
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
- Alternative Name
- TXNRD1 (TXNRD1 Products)
- Synonyms
- TrxR1 Protein, cb682 Protein, fb83a08 Protein, wu:fb83a08 Protein, GB14972 Protein, MGC85342 Protein, NADPH-dependent thioredoxin reductase C Protein, T32G6.20 Protein, T32G6_20 Protein, GRIM-12 Protein, TR Protein, TR1 Protein, TRXR1 Protein, TXNR Protein, Tr Protein, thioredoxin reductase 1 Protein, thioredoxin reductase 1 L homeolog Protein, NADPH-dependent thioredoxin reductase C Protein, ThioRedoXin Reductase Protein, TXNRD1 Protein, txnrd1 Protein, Trxr-1 Protein, txnrd1.L Protein, NTRC Protein, trxr-1 Protein, Txnrd1 Protein
- Background
- TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases. Recombinant human TXNRD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, GRIM 12, GRIM12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase GRIM 12, Thioredoxin reductase TR1, TR 1, TRXR 1, TXNRD 1. NCBI no.: NP_001087240
- Molecular Weight
- 55.7 kDa (508aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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