DDT Protein (AA 1-118) (His tag)

Catalog No. ABIN667020

Product Details

Target: DDT (D-Dopachrome Tautomerase (DDT))

Protein Type: Recombinant

Protein Characteristics: AA 1-118

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This DDT protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: DDT, 1-118aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol

Storage: 4 °C

Target Details

Target: DDT (D-Dopachrome Tautomerase (DDT))

Alternative Name: DDT (DDT Products)

Synonyms: ddt-b Protein, zgc:86714 Protein, wu:fb49f11 Protein, C78655 Protein, DDT Protein, ddt Protein, ddt-a Protein, DDCT Protein, D-dopachrome tautomerase L homeolog Protein, D-dopachrome tautomerase Protein, D-dopachrome tautomerase S homeolog Protein, ddt.L Protein, DDT Protein, ddt Protein, Ddt Protein, ddt.S Protein

Background: DDT is an enzyme that catayzes the tautomerization of D-dopachrome to give 5,6-dihydroxyindole (DHI). This protein belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. It shares a homologous amino acid sequence (33% identical) with the macrophage migration inhibitory factor (MIF) and possesses similar tautomerase activity. In addition, it may functions a proinflammatory cytokine. Recombinant human DDT, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: DDCT, D-dopachtome decarboxylase, D-dopachrome tautomerase, D dopachrome decarboxylase, D dopachrome tautomerase, Phenylpyruvate tautomerase II,. NCBI no.: NP_001346

Molecular Weight: 14.8 kDa(138aa), confirmed by MALDI-TOF