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OTUB1 Protein (AA 1-271) (His tag)

OTUB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667122
  • Target See all OTUB1 Proteins
    OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-271
    Origin
    • 6
    • 3
    • 3
    Human
    Source
    • 9
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This OTUB1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    Otubain 1, 1-271 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product OTUB1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris buffer (pH 8.0) containing 10% glycerol.
    Storage
    4 °C
  • Target
    OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
    Alternative Name
    Otubain 1 (OTUB1 Products)
    Synonyms
    OTB1 Protein, OTU1 Protein, AI850305 Protein, fa19h07 Protein, otub1 Protein, wu:fa19h07 Protein, zgc:92839 Protein, MGC131231 Protein, fb17f04 Protein, otub1l Protein, wu:fb17f04 Protein, zgc:92685 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1 Protein, OTU domain, ubiquitin aldehyde binding 1 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1b Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog Protein, similar to HSPC263 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1a Protein, OTUB1 Protein, Otub1 Protein, otub1b Protein, otub1.L Protein, otub1 Protein, RGD1565010 Protein, otub1a Protein
    Background
    Otubain 1, also known as OTUB1, is a member of the OUT (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with a ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. Recombinant OTUB1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: OTB1, OTU1, Ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTUB1, OTU domain containing ubiquitin aldehyde binding protein 1, Otubain 1, Ubiquitin specific processing protease OTUB1, Ubiquitin thioesterase OTUB1. NCBI no.: NP_060140
    Molecular Weight
    33.4 kDa (291aa), confirmed by MALDI-TOF.
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