OTUB1 Protein (AA 1-271) (His tag)
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- Target See all OTUB1 Proteins
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-271
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This OTUB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Otubain 1, 1-271 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product OTUB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris buffer (pH 8.0) containing 10% glycerol.
- Storage
- 4 °C
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- Target
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
- Alternative Name
- Otubain 1 (OTUB1 Products)
- Synonyms
- OTB1 Protein, OTU1 Protein, AI850305 Protein, fa19h07 Protein, otub1 Protein, wu:fa19h07 Protein, zgc:92839 Protein, MGC131231 Protein, fb17f04 Protein, otub1l Protein, wu:fb17f04 Protein, zgc:92685 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1 Protein, OTU domain, ubiquitin aldehyde binding 1 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1b Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog Protein, similar to HSPC263 Protein, OTU deubiquitinase, ubiquitin aldehyde binding 1a Protein, OTUB1 Protein, Otub1 Protein, otub1b Protein, otub1.L Protein, otub1 Protein, RGD1565010 Protein, otub1a Protein
- Background
- Otubain 1, also known as OTUB1, is a member of the OUT (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with a ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. Recombinant OTUB1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: OTB1, OTU1, Ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTUB1, OTU domain containing ubiquitin aldehyde binding protein 1, Otubain 1, Ubiquitin specific processing protease OTUB1, Ubiquitin thioesterase OTUB1. NCBI no.: NP_060140
- Molecular Weight
- 33.4 kDa (291aa), confirmed by MALDI-TOF.
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