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PFN2 Protein (AA 1-140) (His tag)

PFN2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Catalog No. ABIN667130
  • Target See all PFN2 Proteins
    PFN2 (Profilin 2 (PFN2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-140
    Origin
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 11
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PFN2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PFN2, 1-140 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product PFN2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
    Storage
    4 °C
  • Target
    PFN2 (Profilin 2 (PFN2))
    Alternative Name
    PFN2 (PFN2 Products)
    Synonyms
    D3S1319E Protein, PFL Protein, Pfn Protein, Profilin2 Protein, XProfilin2 Protein, PFN2 Protein, PRO2 Protein, Profilin-2 Protein, pfl Protein, d3s1319e Protein, profilin-2 Protein, F17A13.170 Protein, F17A13_170 Protein, PRF2 Protein, PROFILIN Protein, PROFILIN 2 Protein, profilin 2 Protein, wu:fb01g08 Protein, wu:fb54f09 Protein, wu:fd58f06 Protein, profilin 2 Protein, profilin 2 L homeolog Protein, profilin homolog 2 Protein, Profilin-2 Protein, PFN2 Protein, Pfn2 Protein, pfn2.L Protein, prf2 Protein, pfn2 Protein, pfn-2 Protein
    Background
    PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2. NCBI no.: AAH18049
    Molecular Weight
    17.2 kDa (160aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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