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RUNX3 Protein (AA 53-186) (His tag)

RUNX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN7279042
  • Target See all RUNX3 Proteins
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 53-186
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RUNX3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    RUNX3, 53-186aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product RUNX3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT
    Storage
    4 °C
  • Target
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Alternative Name
    RUNX3 (RUNX3 Products)
    Synonyms
    runxb Protein, RUNX3 Protein, CBFA3 Protein, frrunx3 Protein, runx3 Protein, aml2 Protein, cbfa3 Protein, pebp2ac Protein, AML2 Protein, Cbfa3 Protein, Pebp2a3 Protein, PEBP2aC Protein, runt-related transcription factor 3 Protein, runt related transcription factor 3 Protein, runt related transcription factor 3 L homeolog Protein, runx3 Protein, RUNX3 Protein, runx3.L Protein, Runx3 Protein
    Background
    RUNX3, also known as runt-related transcription factor 3, belongs to the RUNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RUNX3, fused to His-tag at N-terminus, protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RUNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2. NCBI no.: NP_004341
    Molecular Weight
    17.1 kDa (155aa) confirmed by MALDI-TOF
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