beta-2 Microglobulin Protein (AA 21-119) (His tag)
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- Target See all beta-2 Microglobulin (B2M) Proteins
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-119
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This beta-2 Microglobulin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- B2M, 21-119aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product B2M Protein
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beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)B2M Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)B2M Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)B2M Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 1-119) protein (GST tag)B2M Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)Crystallography grade B2M Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl
- Storage
- 4 °C
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- Target
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Alternative Name
- B2M (B2M Products)
- Synonyms
- Ly-m11 Protein, beta2-m Protein, beta2m Protein, bwm Protein, wu:fa94c05 Protein, wu:fb10a09 Protein, b2m-W01 Protein, b2m-W03 Protein, b2m-Z01 Protein, b2m-Z02 Protein, b2m-Z03 Protein, B2M Protein, b2m Protein, B2MG Protein, wu:fb66f11 Protein, wu:fj01f08 Protein, zgc:64161 Protein, b-2-m Protein, beta-2-microglobulin Protein, beta-2 microglobulin Protein, beta-2-microglobulin S homeolog Protein, beta-2-microglobulin, like Protein, B2M Protein, B2m Protein, b2m Protein, b2m.S Protein, b2ml Protein
- Background
- Beta2 microglobulin, also known as B2M, is a component of MHC class I molecules, Involved in the presentation of peptide antigens to the immune system. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Increased production or destruction of these cells causes B2M levels in the blood to increase. This increase is seen in people with cancers involving white blood cells, but it is particularly meaningful in people newly diagnosed with multiple myeloma. Multiple myeloma is a malignancy (cancer) of a certain kind of white blood cell, called a plasma cell. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma or kidney disease. Recombinant B2M protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Beta-2-microglobulin, CDABP0092, HDCMA22P. NCBI no.: NP_004039
- Molecular Weight
- 14.0kDa (120aa), confirmed by MALDI-TOF
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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