GLUL Protein (AA 1-373) (His tag)

Catalog No. ABIN667147

Product Details

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Protein Type: Recombinant

Protein Characteristics: AA 1-373

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GLUL protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: GLUL, 1-373aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 200mM NaCl

Storage: 4 °C

Target Details

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Alternative Name: GLUL (GLUL Products)

Synonyms: GLNS Protein, GS Protein, PIG43 Protein, PIG59 Protein, Glns Protein, glns Protein, glul Protein, pig43 Protein, pig59 Protein, xgs Protein, p42 Protein, MGC64262 Protein, cb195 Protein, cb757 Protein, etID49849.2 Protein, fb39g09 Protein, fd19d09 Protein, gso1 Protein, sb:cb195 Protein, wu:fb39g09 Protein, wu:fd19d09 Protein, fb11d08 Protein, gso2 Protein, hm:zehn1949 Protein, im:7153900 Protein, wu:fb11d08 Protein, glutamate-ammonia ligase Protein, glutamate-ammonia ligase (glutamine synthetase) Protein, type I glutamate--ammonia ligase Protein, glutamate-ammonia ligase L homeolog Protein, glutamate-ammonia ligase (glutamine synthase) Protein, glutamate-ammonia ligase (glutamine synthase) a Protein, glutamate-ammonia ligase (glutamine synthase) b Protein, GLUL Protein, Glul Protein, AMF_RS09530 Protein, glul.L Protein, glul Protein, CNA04370 Protein, glula Protein, glulb Protein

Background: Glutamine synthetase (GLUL), which is therefore able to regulate intracellular concentrations of glutamate. GLUL catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is essential for proliferation of fetal skin fibroblasts and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in GLUL are associated with congenital glutamine deficiency. Recombinant GLUL protein , fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GS, GLNS, Glutamine synthetase, Glutamate-ammonia ligase, Glutamate decarboxylase. NCBI no.: NP_001028216

Molecular Weight: 44.2kDa (393aa), confirmed by MALDI-TOF

Pathways: Positive Regulation of Peptide Hormone Secretion