WARS Protein (AA 1-471) (His tag)

Catalog No. ABIN667149

Product Details

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Protein Type: Recombinant

Protein Characteristics: AA 1-471

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This WARS protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: WARS, 1-471aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS (WARS Products)

Synonyms: GAMMA-2 Protein, IFI53 Protein, IFP53 Protein, zgc:73274 Protein, wars Protein, MGC53671 Protein, WARS Protein, TrpRS Protein, WRS Protein, 85D-WRS Protein, CG9735 Protein, Dmel\\CG9735 Protein, WRS-85D Protein, l(3)03559 Protein, l(3)03560 Protein, l(3)3559 Protein, gamma-2 Protein, ifi53 Protein, ifp53 Protein, GB14934 Protein, ECK3371 Protein, JW3347 Protein, tryptophanyl-tRNA synthetase Protein, tryptophanyl-tRNA synthetase S homeolog Protein, Tryptophanyl-tRNA synthetase Protein, tryptophanyl-tRNA synthetase L homeolog Protein, tryptophan--tRNA ligase, cytoplasmic Protein, WARS Protein, wars Protein, wars.S Protein, Wars Protein, TrpRS Protein, wars.L Protein, LOC727582 Protein, trpS Protein, trpS2 Protein

Background: WARS, also known as tryptophanyl-tRNA synthetase, belongs to the class I tRNA synthetase family. Two forms of tryptophanyl tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. It also regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. Recombinant human WARS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GAMMA-2, IFI53, IFP53, Tryptophanyl-tRNA synthetase, cytoplasmic, TrpRS, hWRS. NCBI no.: NP_776049

Molecular Weight: 55.3 kDa (491aa), confirmed by MALDI-TOF