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HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) protein (His tag)

HTATIP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS- PAGE SDS
Catalog No. ABIN667152
  • Target See all HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Proteins
    HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-242
    Origin
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    His tag
    Application
    SDS-PAGE (SDS)
    Characteristics
    HTATIP2, 1-242aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS- PAGE
    Top Product
    Discover our top product HTATIP2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
    Alternative Name
    HTATIP2 (HTATIP2 Products)
    Synonyms
    htatip2 Protein, MGC89074 Protein, HTATIP2 Protein, fb15b04 Protein, tip30 Protein, wu:fb15b04 Protein, CC3 Protein, SDR44U1 Protein, TIP30 Protein, AW111545 Protein, Cc3 Protein, Tip30 Protein, HIV-1 Tat interactive protein 2 Protein, HIV-1 Tat interactive protein 2 L homeolog Protein, HTATIP2 Protein, htatip2 Protein, Htatip2 Protein, htatip2.L Protein
    Target Type
    Viral Protein
    Background
    HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CC3, TIP30, SDR44U1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30. NCBI no.: AAH15358
    Molecular Weight
    29.3 kDa (262aa), confirmed by MALDI-TOF
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