ITPA Protein (AA 1-194) (His tag)
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- Target See all ITPA Proteins
- ITPA (Inosine Triphosphatase (ITPA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-194
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ITPA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- ITPA, 1-194aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product ITPA Protein
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Inosine Triphosphatase (ITPA) (AA 1-194) protein (GST tag)
ITPA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inosine Triphosphatase (ITPA) (AA 1-194) protein (His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Inosine Triphosphatase (ITPA) (AA 89-193) protein (GST tag)ITPA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inosine Triphosphatase (ITPA) (AA 2-194) protein (His tag)Crystallography grade ITPA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Inosine Triphosphatase (ITPA) (AA 2-198) protein (His tag)Crystallography grade ITPA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Inosine Triphosphatase (ITPA) (AA 3-180) protein (S tag,His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant ≥ 92 % ELISA, WB, SDS, IP
Inosine Triphosphatase (ITPA) (AA 2-198) protein (GST tag,His tag)ITPA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, WB, SDS, IP
Inosine Triphosphatase (ITPA) (Transcript Variant 1) protein (His tag)ITPA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Inosine Triphosphatase (ITPA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ITPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- ITPA (Inosine Triphosphatase (ITPA))
- Alternative Name
- ITPA (ITPA Products)
- Synonyms
- DDBDRAFT_0215619 Protein, DDBDRAFT_0238062 Protein, DDB_0215619 Protein, DDB_0238062 Protein, 2010016I08Rik Protein, AU020102 Protein, Itp Protein, C20orf37 Protein, HLC14-06-P Protein, dJ794I6.3 Protein, ITPase Protein, NTPase Protein, si:ch73-18j6.1 Protein, si:dkey-19f21.1 Protein, inosine triphosphatase Protein, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Protein, Inosine triphosphate pyrophosphatase Protein, inosine triphosphatase S homeolog Protein, itpa Protein, ITPA Protein, LOC733043 Protein, Itpa Protein, pco148511 Protein, itpa.S Protein
- Background
- ITPA, also known as Inosine triphosphate pyrophosphatase, is an enzyme that catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPA can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPA result in ITPA deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts. Recombinant human ITPA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C20orf37, dJ794I6.3, HLC14-06-P, ITPase, My049, OK/SW-cl.9, Inosine triphosphate pyrophosphatase. NCBI no.: NP_258412
- Molecular Weight
- 23.7kDa (215aa) confirmed by MALDI-TOF
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