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SIRT3 Protein (AA 118-399) (His tag)

SIRT3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667166
  • Target See all SIRT3 Proteins
    SIRT3 (Sirtuin 3 (SIRT3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 118-399
    Origin
    • 6
    • 5
    • 4
    • 1
    • 1
    Human
    Source
    • 11
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SIRT3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SIRT3, 118-399aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product SIRT3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    SIRT3 (Sirtuin 3 (SIRT3))
    Alternative Name
    SIRT3 (SIRT3 Products)
    Synonyms
    zgc:158774 Protein, sirtuin Protein, SIR2L3 Protein, 2310003L23Rik Protein, AI848213 Protein, Sir2l3 Protein, sirtuin 3 Protein, sirt3 Protein, SIRT3 Protein, Sirt3 Protein
    Background
    NAD-dependent deacetylase sirtuin-3, mitochondrial, also known as SIRT3, belongs to the sirtuin family of proteins. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have a range of molecular functions and have emerged as important proteins in aging, stress resistance and metabolic regulation. SIRT3 exhibits NAD+-dependent deacetylase activity in the mitochondria. Over-expression of SIRT3 results in increased levels of the mitochondrial uncoupling protein 1. SIRT3 protein levels are also elevated in certain breast cancers. Recombinant human SIRT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SIR2L3, Sirtuin3, NAD-dependent deacetylase sirtuin-3, mitochondrial. NCBI no.: NP_036371
    Molecular Weight
    33.5kDa (303aa) confirmed by MALDI-TOF
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