EDF1 Protein (AA 1-148) (His tag)
-
- Target See all EDF1 Proteins
- EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-148
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EDF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- EDF1, 1-148aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
- Storage
- 4 °C
-
- Target
- EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))
- Alternative Name
- EDF1 (EDF1 Products)
- Synonyms
- edf-1 Protein, mbf1 Protein, EDF-1 Protein, MBF1 Protein, 0610008L11Rik Protein, AA409425 Protein, CAP-19 Protein, zgc:73192 Protein, zgc:86829 Protein, endothelial differentiation related factor 1 S homeolog Protein, endothelial differentiation related factor 1 Protein, endothelial differentiation-related factor 1 Protein, Mbf1p Protein, edf1.S Protein, EDF1 Protein, Edf1 Protein, edf1 Protein, MBF1 Protein
- Background
- Endothelial differentiation-related factor 1, also known as EDF1 may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. Also, EDF1 binds calmodulin thorough its IQ domain and regulates nitric oxide synthase activity through calmodulin sequestration in the cytoplasm. Though ubiquitously expressed, EDF1 is most abundant in adult liver, heart, adipose tissues, intestine and pancreas. Recombinant human EDF1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EDF-1, MBF1, Endothelial differentiation-related factor 1. NCBI no.: NP_003783
- Molecular Weight
- 17.4 kDa (156aa) confirmed by MALDI-TOF
-