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EDF1 Protein (AA 1-148) (His tag)

EDF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667169
  • Target See all EDF1 Proteins
    EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-148
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This EDF1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    EDF1, 1-148aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))
    Alternative Name
    EDF1 (EDF1 Products)
    Synonyms
    edf-1 Protein, mbf1 Protein, EDF-1 Protein, MBF1 Protein, 0610008L11Rik Protein, AA409425 Protein, CAP-19 Protein, zgc:73192 Protein, zgc:86829 Protein, endothelial differentiation related factor 1 S homeolog Protein, endothelial differentiation related factor 1 Protein, endothelial differentiation-related factor 1 Protein, Mbf1p Protein, edf1.S Protein, EDF1 Protein, Edf1 Protein, edf1 Protein, MBF1 Protein
    Background
    Endothelial differentiation-related factor 1, also known as EDF1 may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. Also, EDF1 binds calmodulin thorough its IQ domain and regulates nitric oxide synthase activity through calmodulin sequestration in the cytoplasm. Though ubiquitously expressed, EDF1 is most abundant in adult liver, heart, adipose tissues, intestine and pancreas. Recombinant human EDF1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EDF-1, MBF1, Endothelial differentiation-related factor 1. NCBI no.: NP_003783
    Molecular Weight
    17.4 kDa (156aa) confirmed by MALDI-TOF
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