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CBFB Protein (AA 1-182) (His tag)

CBFB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN7279124
  • Target See all CBFB Proteins
    CBFB (Core-Binding Factor, beta Subunit (CBFB))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-182
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CBFB protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CBFB, 1-182aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product CBFB Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM MES (pH 6.0) containing 0.1 mM PMSF, 10% Glycerol
    Storage
    4 °C
  • Target
    CBFB (Core-Binding Factor, beta Subunit (CBFB))
    Alternative Name
    CBFB (CBFB Products)
    Synonyms
    PEBP2B Protein, Cbfb Protein, pebp2b Protein, Pebp2 Protein, CBFB Protein, unp1266 Protein, cbf-beta Protein, cbfbeta Protein, pea2-beta Protein, pebp2-beta Protein, AI893578 Protein, PEA2 Protein, PEBP2b Protein, Pebpb2 Protein, core-binding factor beta subunit Protein, core binding factor beta subunit Protein, core-binding factor, beta subunit Protein, core-binding factor, beta subunit S homeolog Protein, core binding factor beta Protein, CBFB Protein, Cbfb Protein, cbfb Protein, cbfb.S Protein
    Background
    CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. Recombinant human CBFB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PEBP2B (polyomavirus enhancer binding protein b), PEA2, CBF-beta, Core-binding factor, beta subunit. NCBI no.: NP_001746
    Molecular Weight
    23.6 kDa(202aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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