DR1 Protein (AA 1-176) (His tag)
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- Target See all DR1 Proteins
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-176
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DR1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DR1, 1-176aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DR1 Protein
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TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) protein (His tag)
DR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) protein (GST tag)DR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-100) protein (GST tag)DR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 2-176) protein (His tag)Crystallography grade DR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 2-176) protein (His tag)Crystallography grade DR1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
TATA-Binding Protein-Associated Phosphoprotein (DR1) protein (Myc-DYKDDDDK Tag)DR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 0.1 mM PMSF ,10% Glycerol
- Storage
- 4 °C
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- Target
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- Alternative Name
- DR1 (DR1 Products)
- Synonyms
- BG:DS00929.3 Protein, CG4185 Protein, Dmel\\CG4185 Protein, Dr1 Protein, NC2 beta Protein, Nc2b Protein, dDr1 Protein, dNC2 Protein, wu:fj15f04 Protein, zgc:152914 Protein, 1700121L09Rik Protein, Dr1l Protein, NC2 Protein, NC2beta Protein, NC2-BETA Protein, Negative Cofactor 2beta Protein, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN Protein, TATA-binding protein-associated phosphoprotein Protein, putative tata-binding protein-associated phosphoprotein Protein, down-regulator of transcription 1 Protein, down-regulator of transcription 1, TBP-binding (negative cofactor 2) Protein, NC2beta Protein, ECU11_0730 Protein, EDI_229030 Protein, PTRG_08168 Protein, Smp_160150 Protein, EBI_26279 Protein, EBI_23074 Protein, VDBG_02216 Protein, dr1 Protein, Dr1 Protein, DR1 Protein
- Background
- DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I. Recombinant human DR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: NC2, NC2-BETA, Down-regulator of transcription 1, TBP-binding. NCBI no.: NP_001929
- Molecular Weight
- 21.6 kDa(196aa), confirmed by MALDI-TOF
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