QPRT Protein (AA 1-297) (His tag)
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- Target See all QPRT Proteins
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-297
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This QPRT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- QPRT, 1-297aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product QPRT Protein
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Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (His tag)
QPRT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (GST tag)QPRT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) protein (GST tag)QPRT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (Strep Tag)Crystallography grade QPRT Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-299) protein (Strep Tag)Crystallography grade QPRT Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) protein (Myc-DYKDDDDK Tag)QPRT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Alternative Name
- QPRT (QPRT Products)
- Synonyms
- ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
- Background
- Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Recombinant human QPRT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nicotinate nucleotide pyrophosphorylase carboxylating, Quinolinate phosphoribosyltransferase , QPRTase, QAPRTase. NCBI no.: NP_055113
- Molecular Weight
- 32.9 kDa (317aa), confirmed by MALDI-TOF
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