Deoxyuridine Triphosphatase (DUT) (AA 70-252) protein (His tag)
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- Target See all Deoxyuridine Triphosphatase (DUT) Proteins
- Deoxyuridine Triphosphatase (DUT)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 70-252
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Characteristics
- DUT, 70-252aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS – PAGE
- Top Product
- Discover our top product DUT Protein
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Deoxyuridine Triphosphatase (DUT) (AA 1-164) protein (His tag)
DUT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Deoxyuridine Triphosphatase (DUT) (AA 70-252) protein (His tag)DUT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Deoxyuridine Triphosphatase (DUT) (AA 68-164) protein (GST tag)DUT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 41-122) protein (GST tag)DUT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 1-252) protein (GST tag)DUT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 1-278), (full length) protein (His-SUMO Tag)DUT Origin: Epstein-Barr Virus (EBV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Deoxyuridine Triphosphatase (DUT) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DUT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- Deoxyuridine Triphosphatase (DUT)
- Alternative Name
- DUT (DUT Products)
- Synonyms
- BcDNA:LD08534 Protein, CG4584 Protein, Dmel\\CG4584 Protein, LD08534 Protein, UTPase Protein, anon-SAGE:Wang-077 Protein, dUTPase Protein, Tb07.27E10.390 Protein, dutpase Protein, 5031412I06Rik Protein, 5133400F09Rik Protein, D2Bwg0749e Protein, Dutp Protein, PIP4 Protein, deoxyuridine triphosphatase Protein, Deoxyuridine triphosphatase Protein, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 Protein, involved in nucleotide metabolism Protein, tegument protein Protein, dUTPase Protein, deoxyuridine triphosphatase L homeolog Protein, DUT Protein, dUTPase Protein, P18 Protein, AlHV1gp51 Protein, UL50 Protein, HVT058 Protein, ORF9 Protein, ORF8 Protein, U45 Protein, GAMMAHV.ORF54 Protein, Tc00.1047053509151.130 Protein, Tc00.1047053508175.160 Protein, Tb927.7.5160 Protein, dut.L Protein, Dut Protein
- Target Type
- Viral Protein
- Background
- DUT, also known as dUTP pyrophosphatase, is a ubiquitous enzyme that functions in nucleotide metabolism. This protein, in the presence of magnesium ions, is responsible for hydrolyzing dUTP to dUMP and diphosphate. This reaction is important for keeping the intracellular dUTP concentration low so that uracil does not become incorporated into DNA. Extensive incorporation of uracil into DNA can ultimately lead to cell death. This suggests that DUT is essential for cell viability, further implying that it is a potential target for anticancer therapy. Recombinant human DUT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: dUTPase, dUTP pyrophosphatase, FLJ20622, dUTPase, dUTP pyrophosphatase, FLJ20622. NCBI no.: NP_001020419
- Molecular Weight
- 21.6 kDa (204aa), confirmed by MALDI-TOF
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