HARS1/Jo-1 Protein (AA 1-509) (His tag)
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- Target See all HARS1/Jo-1 (HARS1) Proteins
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-509
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HARS1/Jo-1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HARS, 1-509aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS – PAGE
- Top Product
- Discover our top product HARS1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- Alternative Name
- HARS (HARS1 Products)
- Synonyms
- HRS Protein, USH3B Protein, MMHRS Protein, Dnd1 Protein, HARSL Protein, histidyl-tRNA synthetase Protein, HARS Protein, Hars Protein
- Background
- HARS, also known as Histidyl-tRNA synthetase, function to catalyze the aminoacylation of tRNAs by their corresponding amino acids. HARS is from the class II family of aminoacyl-tRNA synthetases. It is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. HARS is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Recombinant human HARS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FLJ20491, HRS, HisRS, Histidine--tRNA ligase, Histidyl-tRNA synthetase, cytoplasmic. NCBI no.: NP_002100
- Molecular Weight
- 59.4 kDa (532aa), confirmed by MALDI-TOF
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