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LIF Protein (AA 23-202) (HIS-GST)

LIF Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667245
  • Target See all LIF Proteins
    LIF (Leukemia Inhibitory Factor (LIF))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-202
    Origin
    • 21
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Source
    • 20
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This LIF protein is labelled with HIS-GST.
    Application
    SDS-PAGE (SDS)
    Characteristics
    LIF, 23-202aa, Human, His-GST tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product LIF Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 50mM NaCl
    Storage
    4 °C
  • Target
    LIF (Leukemia Inhibitory Factor (LIF))
    Alternative Name
    LIF (LIF Products)
    Synonyms
    CDF Protein, DIA Protein, HILDA Protein, MLPLI Protein, LIF, interleukin 6 family cytokine Protein, leukemia inhibitory factor Protein, LIF Protein, Lif Protein
    Background
    Leukemia inhibitory factor, also known as LIF, is a pleiotropic cytokine that is expressed by a wide variety of cells including activated T lymphocytes, monocytes, mast cells and neuronal cells. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Recombinant human LIF protein, fused to His GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Leukemia inhibitory factor, CDF, HILDA, DIA, D FACTOR, MLPLI, Emfilermin. NCBI no.: NP_002300
    Molecular Weight
    47.2 kDa (415aa) confirmed by MALDI-TOF
    Pathways
    JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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